Digital commerce has emerged as a critical driver of small enterprise transformation in developing economies. In India, the introduction of the Open Network for Digital Commerce (ONDC) represents a policy initiative aimed at democratizing digital marketplaces and expanding participation among micro, small, and medium enterprises (MSMEs). Despite its policy significance, empirical evidence on the economic impact of digital commerce adoption in emerging regional markets remains limited. This study examines the relationship between digital adoption and MSME performance within sub-urban commercial environments. Building on the Technology Acceptance Model, Diffusion of Innovations theory, and the Digital Divide framework, the research develops a conceptual model linking technological capability, digital adoption, and vendor performance. Using a mixed analytical approach combining descriptive analysis, econometric modeling, and interaction-based regression techniques, the study evaluates how smartphone access, education, and digital commerce adoption influence revenue outcomes among small enterprises. The empirical results indicate that digital adoption significantly improves vendor revenue growth and market participation, while smartphone access and education act as enabling factors facilitating digital integration. Interaction analysis further reveals that the economic returns from digital adoption vary across regional market environments, highlighting the role of infrastructure and institutional context in shaping digital transformation outcomes. These findings suggest that digital commerce initiatives can substantially enhance MSME competitiveness, but their effectiveness depends on complementary investments in digital literacy, infrastructure development, and localized support systems. The study contributes to the emerging literature on inclusive digital economies by providing empirical evidence on the mechanisms through which open digital commerce ecosystems influence small enterprise growth in developing regional markets.